Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p229 | Energy metabolism and bone, fat and bone | ECTS2016

Impaired adipose tissue inflammation results in increased bone mineral density in mice

Grahnemo Louise , Gustafsson Karin , Asterholm Wernstedt Ingrid , Lagerquist Marie

Obesity, diabetes, and high fracture risk is linked, but the mechanism is unclear. However, impaired acute adipose tissue inflammation may be a common denominator for these conditions. Impaired adipose tissue inflammation leads to low adipogenesis, insufficient adipose expansion, and signs of diabetes.The aim of this study was to investigate if the low adipogenesis induced by impaired adipose tissue inflammation is coupled to increased osteoblastogenesis...